Description
Description
Formally as active B complex
Benefits
- Provides the natural and most bioactive form of folate, Quatrefolic folate (6S)-5-MTHF, with no synthetic or racemic components
- Quatrefolic folate supplementation has a greater increase in plasma folate compared to folic acid and calcium 5-MTHF
- Contains most bioactive and bioavailable forms of each B vitamin, including methylcobalamin (B12), riboflavin 5’-phosphate (B2), and pyridoxal 5’-phosphate (B6)
- Broad-spectrum B complex, with inositol, biotin, and choline
- Suitable for vegetarians/vegans
Feature Summary
Active B Complex provides the most biologically active forms and clinically relevant doses of a unique B vitamin combination. Quatrefolic folate provides (6S)-5-methyltetrahydrofolic acid (MTHF), the active form of folate at the cellular level, which is found in circulation and is the form able to cross the blood brain barrier. This form of folate bypasses enzymatic conversion by methylene tetrahydrofolate reductase (MTHFR), an enzyme with common genetic polymorphisms known to impair activity. Quatrefolic acid administration has been associated with higher peak (6S)-5-MTHF levels than both folic acid and calcium 5-MTHF, with higher plasma folate levels even in those with high functioning MTHFR polymorphisms. It also shows a more rapid repletion of folate levels among pregnant women than folic acid, along with the ability to lower homocysteine without masking a B12 deficiency.
In addition to superior folate bioavailability, Active B Complex contains superior forms of each B vitamin. Benfotiamine is a lipid-soluble form of vitamin B1 with higher bioavailability than thiamine. Riboflavin 5’-phospate and pyridoxal 5’-phosphate (PLP) are biologically active forms of B2 and B6. PLP is the most important member of the B6 group and is the active coenzyme for more than 100 enzymes, bypassing hepatic conversion to an active form.
Active B Complex also provides clinically relevant doses of methylcobalamin, niacin, pantothenic acid, biotin, choline, and inositol.
Exp: 10/2027
Supplement Facts
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